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Esomeprazole (Enteric-Coated) & Domperidone (Sustained-Release) Capsules

Esomeprazole (Enteric-Coated) & Domperidone (Sustained-Release) Capsules: Harmonizing Acid Control and Gastric Motility

Introduction: Esomeprazole (Enteric-Coated) & Domperidone (Sustained-Release) Capsules combine the therapeutic benefits of Esomeprazole, a proton pump inhibitor (PPI), and Domperidone, a dopamine antagonist. This unique formulation is designed to provide comprehensive relief from gastric acidity and address motility disorders.

Key Ingredients:

  1. Esomeprazole: An enteric-coated proton pump inhibitor that effectively reduces stomach acid production by inhibiting the proton pump in the stomach lining.

  2. Domperidone: A sustained-release formulation of this dopamine antagonist enhances gastric motility, facilitating the movement of food through the digestive system.

Indications: Esomeprazole & Domperidone Capsules are indicated for the treatment of conditions including:

  1. Gastroesophageal Reflux Disease (GERD): Heals and prevents the recurrence of erosive esophagitis caused by excessive stomach acid.

  2. Dyspepsia: Provides relief from symptoms such as bloating, discomfort, and heartburn.

  3. Delayed Gastric Emptying: Aids in promoting gastric motility, particularly in cases where delayed emptying is a concern.

Mechanism of Action:

  • Esomeprazole: Reduces gastric acid production by inhibiting the proton pump, providing effective and sustained relief from acidity.

  • Domperidone: Enhances gastric motility by blocking dopamine receptors, promoting the movement of food through the digestive tract.

Dosage and Administration:

  • Dosage is determined by healthcare providers based on the individual’s condition.

  • Capsules are usually taken orally, with or without food, as directed by the healthcare provider.

Precautions:

  • Patients should inform their healthcare provider of any existing medical conditions or medications, especially those affecting the heart.

  • Caution is advised in patients with known risk factors for heart rhythm disturbances.

Side Effects: Common side effects may include:

  • Gastrointestinal upset
  • Headache
  • Dizziness

Patients should promptly report any severe or persistent side effects to their healthcare provider.

Contraindications: Esomeprazole & Domperidone Capsules may not be suitable for individuals with:

  • Known hypersensitivity to either Esomeprazole or Domperidone.

  • Pre-existing cardiac conditions or those at risk of heart rhythm disturbances.

Conclusion: Esomeprazole (Enteric-Coated) & Domperidone (Sustained-Release) Capsules offer a dual-action approach to address gastric acidity and motility issues. Patients are encouraged to adhere to prescribed dosages, follow their healthcare provider’s recommendations, and promptly report any concerns or adverse effects.

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